Company:

Mallinckrodt

Antitussive + antihistamine

Hydrocodone bitartrate 10mg, chlorpheniramine maleate 8mg; as polistirex; ext-rel caps; contains alcohol.

TUSSICAPS 5mg/4mg CIII

Hydrocodone bitartrate 5mg, chlorpheniramine maleate 4mg; as polistirex; ext-rel caps; contains alcohol.

Cough and upper respiratory symptoms.

TussiCaps combines the opioid analgesic, hydrocodone, with the H1 receptor antagonist, chlorpheniramine. Hydrocodone is a semi-synthetic codeine derivative with analgesic, antitussive, and CNS effects. Chlorpheniramine is an antihistamine agent with anticholinergic and sedative activity. It prevents released histamine from dilating capillaries and causing edema of the respiratory mucosa.

1 cap (10mg/8mg) every 12hrs; max: 2caps/24hrs.

<6yrs: see Contraindications. 6–11yrs: 1 cap (5mg/4mg) every 12hrs; max: 2caps/24hrs.

Children <6yrs of age (risk of fatal respiratory depression).

Respiratory depression. Post-op. Pulmonary disease. Head injury. Increased intracranial pressure. Glaucoma. Asthma. GI or GU obstruction. Acute abdomen. Severe hepatic or renal impairment. Hypothyroidism. Addison’s disease. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.

Additive CNS depression with alcohol, other CNS depressants, tricyclic antidepressants, MAOIs. Paralytic ileus with concurrent anticholinergics.

Nausea, vomiting, CNS and respiratory depression, ureteral and vesical sphincter spasm, chest tightness, abuse potential, anticholinergic effects, rash, pruritis.

Caps—20, 100

10/02/08